A specialized form of pattern ERG is the multifocal ERG (mfERG) which allows for a different spatial understanding of abnormalities in the central part of the retina. The mfERG is performed with a similar protocol to the PERG, but the light stimulus displays an array of hexagons that flicker between white and black in a pseudo-random sequence. Depending on the protocol used, multiple ERGs can be produced and associated with regions of the retina.
mfERG is fairly localized and sensitive, as demonstrated by its ability to detect the difficult-to-find blind spot in the retina. The spatial aspect of the mfERG is especially useful when diagnosing retinal dysfunction that is localized to specific areas, as is usually the case in conditions like Stargardt’s Disease/fundus flavimaculatus or Plaquenil toxicity. The toxic effects of Plaquenil (hydroxychloroquinone) create a distinctive pattern of damage, so mfERGs are recommended for all patients in Plaquenil therapy to detect retinal harm as quickly as possible. In disorders that primarily affect the macula and do not cause morphological changes, such as cone-rod dystrophy or early Stargardt dystrophy, mfERG is a highly valuable diagnostic tool. The mfERG is best for measuring dysfunction of the inner retina and is not sensitive to abnormalities in the ganglion axon.
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Warning: This product can expose you to chemicals including lead, which is known to the State of California to cause cancer and birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
The table below lists substances which may be contained within LKC’s RETeval and RETevet products. Substances listed as Type 1 are within permissible levels in one or more of LKC’s products. Substances listed as Type 2 are used in the production of some components used in LKC products and may be present at trace levels, but are typically destroyed during processing.
RETeval and RETevet Devices
|Listed as causing:
|Cancer Developmental Toxicity Male Reproductive Toxicity Female Reproductive Toxicity
|Cancer Female Reproductive Toxicity
|Male Reproductive Toxicity